Annonces professionnelles

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Post-doctoral Positions in Skeletal muscle Stem Cells and molecular medicine

The candidates will be involved in (1) Analysing signalling pathways involved in early activation of skeletal muscle stem cells, (2) Analysing the impact of obesity and inflammation for muscle stem cells biology during skeletal muscle growth, regeneration and aging, (3) Performing preclinical modelling and therapeutic research in skeletal muscle diseases, including sarcopenia in obese patients. In addition the candidate will help to train ad supervise Master and PhD students.

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Universite_savoie

Thèse : Approches thérapeutiques pour la dystrophie Facioscapulohumerale

La FSHD est l’une des dystrophies musculaires les plus fréquentes et jusqu’à présent il n’existe aucun traitement curatif ou préventif. La FSHD est caractérisée par la perte de marques épigénétiques répressives au niveau da partie sub-télomérique du chromosome 4 (au niveau des répétitions D4Z4) conduisant à l’expression aberrante du facteur de transcription DUX4. Nous avons récemment publié une nouvelle approche thérapeutique visant l’ARNm DUX4 in vitro et le but du projet est d’évaluer cette approche in vivo en utilisant un modèle de souris exprimant DUX4 déjà disponible au laboratoire.

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UNH

L’ école doctorale sciences de la vie, sante, agronomie, environnement recherche des candidats pour une thèse
Titre de la thèse : Régulation d’enzymes d’ubiquitination impliquées dans l’atrophie musculaire

L’Ecole Doctorale des Sciences de la Vie, Santé, Agronomie, Environnement représente un potentiel de plus de 300 chercheurs habilités à diriger des recherches, 28 laboratoires d’accueil et environ 215 doctorants.
L’Ecole Doctorale des Sciences de la Vie, Santé, Agronomie, Environnement possède la particularité d’être rattachée à deux établissements co-accrédités, l’Université Blaise Pascal et l’Université d’Auvergne.

Le sujet de thèse proposé vise à répondre à ces questions pour 1 ou 2 des couples E2-MuRF1 identifiés. L’influence de ces couples sur la dégradation des protéines contractiles sera testée par co-expression des protagonistes en cellules HEK, suivie de western blot afin d’évaluer la dégradation du substrat. Les autres techniques utilisées seront des techniques d’interaction protéines-protéines (Résonnance plasmonique de surface [Biacore], split-GFP en cellules de mammifères, chromatographie d’exclusion), ainsi que des techniques de (co-)localisation cellulaire en myotubes (GFP ou immuno-marquage).

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filnemusChargée de Mission pour la filière de santé maladies rares maladies neuromusculaires : FILNEMUS 

Laboratoire de génétique moléculaire – CHU de Montpellier

Le chargé de mission participera à 1) la coordination de la mise en place d’une organisation nationale homogène du NGS ciblé de gènes des maladies neuromusculaires 2) et à l’évaluation de l’efficacité diagnostique de cette stratégie pour la Filière FILNEMUS.

Les fonctions principales seront:
– Organisation des actions au sein des laboratoires en fonction des objectifs, en lien avec les coordonnateurs:
– diffusion aux laboratoires des actions à mener avec les objectifs et délais impartis,
– collecte des documents remplis par les laboratoires
– Mise en forme des documents, synthèse.
– Diffusion éventuelles des documents de synthèse pour avis et validation aux personnes concernées (définies pas le coordonnateur)
– Diffusion des documents validés pour mise en ligne sur le site Internet de Filnemus.
– Organisation logistique (réunions téléphoniques régulières) et compte rendus écrit de chaque réunion de SG et de coordonnateurs.

Compétences requises
Niveau Ingénieur de Recherche (Thèse de sciences en génétique moléculaire indispensable)
Qualités relationnelles, sens de l’organisation, très bon niveau rédactionnel indispensable.

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Neuromuscular Disease Training Program

The Neuromuscular diseases and ALS department of Nice University Hospital Center, an outstanding research center devoted to understanding neuromuscular diseases and development of innovative clinical therapies for neuromuscular disorders, is welcoming applications for position as neurologist fellow in an international exchange program for 6 month to 1 year for training in neuromuscular diseases.

The fellow will take part in clinical activity and training activity on our institute and on the CRMR’s specialized platforms (anatomo-pathology, electrophysiology, ultra-sound/MRI) as well as in basic and/or clinical research projects focused on genetic and epigenetic of neuromuscular diseases, development of cellular and animal models

Duration: 6 month up to 1 year

Profile: Candidates should speak French and English to take part to clinical training, French or English to take part to basic research projects. This training is highly recommended for young neurologist in training wishing to spend a year in a foreign Institution and European PhD candidates

Click here to view the full Job Description


PhD position in Cell Biology and Biophysics at Institut Jacques Monod (Paris, France)

Modulation of cell-cell adhesion in epithelial cells In monolayered epithelia, differentiated cells display a specific apico-basal organization. To maintain cell polarization and cohesion of neighbouring cells, cells developed diverse adhesion complexes. However, the epithelial monolayer is subjected to remodelling during organism development or tissue repair. Consequently, the epithelium has to constantly maintain its apico-basal compartimentation and to collectively adapt to its microenvironment to maintain its polarized and cohesive state.
Our team is generally interested in understanding basic mechanisms underlying cellcell adhesion in epithelial cells. We couple the use of human or mouse cell cultures and microfabrication techniques to answer basic questions in epithelial morphogenesis. Association of adhesion molecules, their lateral membrane dynamics as well as connection to cytoskeletal networks are investigated using high resolution microscopy in living cells.

You can find more information on our current research on our web page : click here

We are seeking to recruit a motivated pre-graduate candidate with background in cell/developmental biology and/or biophysics. The PhD student will benefit from an interdisciplinary environment with expertise in cell biology, biochemistry, developmental biology and imaging, and will have access to leading edge equipment.

Applicants should send a motivation letter, a CV and a referee name to :
Contact : Delphine Delacour delphine.delacour@ijm.fr, Institut Jacques Monod, « Cell Adhesion and Mechanics » team

Click here to view the full Job Description


Pierre_Fabre_Laboratoire

Pierre Fabre Postdoctoral Fellowship Program

Pierre Fabre is launching its postdoctoral fellowship program to accelerate our pursuit of solutions to critical questions driving the identification of transformative therapies for patients.

We are looking to fill several postdoc positions in the following areas:
• Dissecting the mechanisms of inflammation in the tumor microenvironment
• Developing preclinical models of cancer that translate into patient outcomes
• Protein engineering of next generation immunocytokine therapeutics
• Discovery and synthesis of next generation cytotoxic payloads

We are looking for highly motivated individuals passionate about joining our pharmaceutical R&D organization to invent and develop the future therapeutic solutions for the sake and benefits of patients.

Click here to view the full Job Description


HR-Excellence

Postdoctoral Scientist in Developmental and Stem Cell Biology

The role
This new post allows a talented, driven and high-calibre scientist to develop an exciting project aimed at investigating the earliest specification events giving rise to mesodermal lineages.

Essential selection criteria

  • A PhD or near to completion in a relevant area, together with relevant experience.
  • A strong publication record in peer-reviewed journals (at least two second tier or one first tier first author publication(s)).
  • Excellent communication skills, including the ability to write for publication, present research proposals and results, and represent the research group at meetings.
  • Excellent organisational and time-management skills with a methodical and careful approach to working in the laboratory.
  • Experience in dissecting and working with mouse embryos.
  • Experience with independent multi-colour FACS analysis.
  • Experience in molecular techniques such as molecular cloning, qRT-PCR, RNA-seq, CRISPR/Cas9 genome engineering etc.
  • Ability to manage and independently drive, innovate (generate novel scientific ideas) and complete own research and associated activities.
  • Ability to learn and assimilate new ideas and advice. Ability to contribute ideas for new research projects and research income generation Communicate results clearly and succinctly in presentations, manuscripts and grant applications.
  • Ability to work as a team member and to work independently as required.

 Click here to view the full Job Description


ETH Zurich

 

Assistant Professor (Tenure Track) of Movement and Exercise Biology

The Department of Health Sciences and Technology (www.hest.ethz.ch) of ETH Zurich invites applications for an assistant professorship with tenure track in Movement and Exercise Biology. The research area focuses on molecular, genetic, cellular or systemic mechanisms that are involved in mediating the body’s response to exercise and movement training.

Click here to view the full Job Description


Faculté de médecine de Saint-Etienne

 

Le Laboratoire Interuniversitaire de Biologie de la Motricité (EA7424, Université Jean Monnet Saint Etienne) propose un sujet de thèse intitulé : Cachexie musculaire associée au cancer du colon: déterminants moléculaires, capacité fonctionnelle musculaire et niveau d’activité physique. Ce projet sera dirigé par Damien Freyssenet.

Le ou la candidat(e) devra posséder un très bon niveau académique (mentions dans le parcours). La maitrise des outils de biologie (RT-qPCR, enzymologie, western blot, immunohistochimie, microscopie en épifluorescence) est nécessaire. Il ou elle devra également avoir une expérience dans l’utilisation des outils d’estimation du niveau d’activité physique (bracelet connecté, questionnaire d’activité, …), une solide formation statistique (formation au logiciel R souhaitable) et un bon niveau d’anglais (B2 minimum). Il ou elle devra également posséder les qualités humaines nécessaire à la relation avec le patient.

 

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university_liverpool

Job Specification
Postdoctoral Research Associate Grade 7
Biochemistry
007108
£32,958 – £36,001 pa
23-May-2017
We are looking to recruit a postdoctoral fellow for an exciting project funded by the Medical Research Council (MRC) and by three charities (Charlie’s Fund, Duchenne UK and Joining Jack) aimed at testing a novel therapeutic approach for the treatment of Duchenne muscular dystrophy. The successful candidate will be able to demonstrate excellent motivation, good knowledge of the literature on muscular dystrophy and an interest in pre-clinical studies. We would particularly like to encourage applicants with experience in studies involving mice and histology. Previous experience with preclinical studies is desirable. The successful candidate should have a PhD in a relevant biological science discipline. The work will be based in well-equipped laboratories in the Institute of Integrative Biology (https://www.liverpool.ac.uk/integrative-biology/), which hosts a cutting-edge Centre for Cell Imaging (http://cci.liv.ac.uk/) and is associated with a state-of-the-art Animal Facility and a word-class Centre for Preclinical Imaging (https://www.liverpool.ac.uk/technology-directorate/facilities/). The post is available until 31 August 2018.

 

Click here to view the full Job Description


 

Laboratoire Interuniversitaire de Biologie de la Motricité (LIBM) de l’Université Savoie Mont Blanc
siseo.univ-savoie.fr

 

Ce projet repose sur un travail collaboratif, initié par de précédentes thèses et poursuivi ainsi, entre le LIBM (EA 7424) des sites Université Savoie Mont Blanc de Chambéry et Université Jean Monnet de Saint-Etienne, et le CRMBM (Centre de Résonance Magnétique Biologique et Médicale, CNRS, UMR 7339) d’Aix-Marseille Université.
La clôture des candidatures auprès du directeur (L. Messonnier) et des co-directeurs (L. Féasson et D. Bendahan) est fixée au 31 mai 2017 12:00
Dès le 1er juin, un(e) candidat(e) sera retenu(e), et le dossier du couple projet/candidat(e) sera officiellement déposé le 5 juin à l’ED.
Le projet sera ensuite défendu par le/la candidat(e) devant le conseil restreint de l’ED SISEO lors d’une audition qui aura lieu le lundi 19 ou le mardi 20 juin 2017 à Chambéry (centre ville, Rue Marcoz, siège de l’USMB).

Dès à présent, les candidat(e)s sont vivement encouragé(e)s à prendre contact avec les responsables scientifiques, qui restent à leur entière disposition.

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International PostDoctoral Program 2017
Application deadline : 31 May 2017

 

Genethon, a leading organisation in gene therapy for rare genetic diseases is seeking highly motivated post-doctoral fellows. Positions are available for a period of three years (37-41 k€ annual gross income depending on qualifications and experience). A list of projects is available on our website : click here

Eligibility
Candidates should meet the following criteria:
➢ Maximum three years of post-doctoral experience
➢ Interest in basic and translational research of genetic diseases
➢ Solid background in cell and molecular biology
➢ Good publication record and excellent references
➢ Excellent English knowledge
➢ Be creative and capable of developing a competitive research project in autonomy under the supervision of a team leader.

 

Click here for more information 


 

PhD position at IGBMC-Strasbourg-France

Novel therapeutic approaches for Myopathies

 

Myopathies are severe inherited diseases having a strong impact on patient’s quality of life, on their family and on our health care system. They manifest with muscle weakness and sometimes pain and may lead to a decrease in respiratory function, autonomy and lifespan. They can affect individuals from birth or in adulthood. There is no specific therapy for most of these diseases.

The aim of the PhD project is to validate novel therapeutic proof-of-concepts for different myopathies. Previously, a therapeutic target was identified (see Cowling et al., 2014). Previous work has identified a therapeutic target, which downregulation allows the prevention and the reversion of a severe progressive myopathy in animal models. We now aim to validate this approach for other myopathies, using molecular and cellular biology, physiopathology and omics-based integrated analyses. All tools (including chemicals to modulate the therapeutic target), models and expertise required for this project are already available in our team or existing.

This project should lead to the validation of novel therapeutic strategies for several myopathies and potentially identify disease biomarkers crucial for future human trials. It will be conducted at IGBMC together with the biotech company Dynacure which is developing such strategies towards the clinic.

A 3 year salary is available through a CIFRE funding. Start date can be from June 2017.

Candidate profile: holding a Master degree in biology, with previous training in a research lab and interest in human disease and therapies. The ability to acquire independence and be highly motivated to learn and to work in an international team is essential. Previous expertise in pathology and/or physiology will be an asset. French speaking is not a requirement.

The IGBMC institute is one of the main European center in medical research and offers a unique environment with 50 research teams, state-of-the-art platforms, a PhD program and 45 different nationalities.
Dynacure is a biotech company developing new treatments for patients affected by serious orphan disorders. Dynacure is currently focusing on Centronuclear Myopathies (CNM) in collaboration with Ionis Pharmaceuticals, the leading biopharmaceutical company in RNA-targeted drug discovery.

Strasbourg is a cosmopolitan city near Germany and less than 2 hours from Paris’ center by train.

References:
Cowling et al. J Clin Invest. 2014 Mar 3;124(3):1350-63.
www.igbmc.fr/Laporte/
www.dynacure.fr/

Applications: Candidates are invited to apply by sending a curriculum vitae, a cover letter, and contact details for two referees to:
info@dynacure.fr

 


 

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Postdoctoral Fellow – Skeletal Muscle Molecular Physiology

University of Wisconsin–Madison

United States, Madison

Job description

Highly motivated scientists are invited to apply for a postdoctoral position in Dr. Hornberger’s laboratory at the University of Wisconsin – Madison.

The research in Dr. Hornberger’s lab is focused on defining the molecular events through which mechanical signals regulate skeletal muscle mass.

The successful applicant will have unique access to global phosphoproteomic datasets that are being generated from skeletal muscles that have been subjected to a bout of exercise (endurance vs. resistance), or a decrease in mechanical loading (e.g., immobilization). Using these datasets, the primary focus of the research will involve the use of bioinformatics-based approaches to identify signaling events of interest, and then the application of various molecular interventions to test the functional significance of the signaling events that have been identified.

The position offers exciting avenues for publication, will foster the individual’s career development, and provide salary / benefits at a level that is consistent with current NIH postdoctoral stipends.

Desired skills and experience

Essential Skills and Requirements:

  • The position requires a 2 year commitment
  • Candidates must hold a PhD or MD/PhD, have a record of productive research, and possess the ability to work in both independent and collaborative settings
  • Experience with at least some of the following techniques is required;
    • Bioinformatics
    • Animal models of exercise and / or disuse
    • Transfection-based assays
    • Protein biochemistry / cellular signaling
    • Other molecular techniques such as cloning and site-directed mutagenesis

If interested, please apply online via the « Apply for this job » button and submit a cover letter that summarizes your research interest, a CV, and the contact information for at least three references.

—————————————————————————

Damien Bachasson, PhD
Project Scientist
Institute of Myology | Neuromuscular Physiology Laboratory
Groupe hospitalier Pitié-Salpêtrière
Batiment Babinski
47-83 Boulevard de l’Hôpital
75651 PARIS CEDEX 13
Cell: +33 6 20 26 56 69,  Fax : +33 1 42 16 58 81

 


Les Hospices Civils de Lyon recherchent un neurologue pour assurer le développement et la structuration de la prise en charge des pathologies Neuromusculaires et de la SLA à l’hôpital Neurologique de Lyon

Le (La) candidat (e) devra disposer d’un potentiel hospitalo-universitaire affirmé, (mobilité internationale réalisée, thèse de sciences, projet d’HDR ou HDR obtenue) afin de répondre aux enjeux de cette activité et à l’ambition des HCL de s’affirmer comme un pôle d’excellence pour cette discipline.

Les candidat(s)(es) devront démontrer, à travers leur parcours et leur vision large de la discipline neuromusculaire, leur potentiel à diriger cette activité au sein d’une équipe de praticiens expérimentés. Ils devront également démontrer leur potentiel pour assurer la mission d’enseignement et de formation, élément indispensable pour la reconnaissance et l’attractivité de la discipline.

En plus de ses compétences cliniques, de sa volonté d’assurer des responsabilités notamment de management en lien étroit avec le chef de service, les candidat-e-s devront démontrer des aptitudes à la conduite de projet de recherche ambitieux en collaboration avec un institut de recherche majeur dans ces pathologies, l’INMG.

Les candidats devront maitriser parfaitement la langue française.

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Ph.D. Applications Specialist

We are looking for a M.S. or Ph.D.-level scientist or engineer with an interest in scientific microscopic imaging to fulfill the role as an Applications Specialist in our joint labs in the Departments of Cell Biology and Bioinformatics.The successful candidate will conduct imaging projects using advanced high resolution microscopes (including light-sheet, super-resolution, adaptive optics, 2-photon intravital and TIRF). The tasks will involve assay optimization using a broad range of specimens, from conventional 3D cell culture systems to zebrafish and mouse xenografts, setting up long term image acquisitions, data quality control and periodic instrument alignment / maintenance. The candidate should ideally have a M.Sc.or PhD in cell biology, biophysics or engineering, and documented experience with 3D microscopy of live specimens. Previous experience with advanced microscopy methods and enthusiasm for biological imaging is strongly encouraged. We offer a unique and diverse environment where biologists, physicists, engineers and computer scientists work together to establish patho-physiologically relevant cell biology, with an emphasis on cancer-related processes.

More information on our research and lab teams can be found at:

http://www.utsouthwestern.edu/labs/fiolka/

http://www.utsouthwestern.edu/labs/danuser/

The position is available immediately and applications can be addressed to:
Reto Fiolka
Assistant Professor in Cell Biology
UT Southwestern
Dept of Cell Biology
Room NL 5.120GC
6000 Harry Hines Blvd
Dallas TX 75390
Phone: 214 648 4596
Reto.Fiolka@UTsouthwestern.edu

 

 


 

 Comportements mécaniques et méthodes numériques pour la biomécanique

Profil recherche :
Le maître de conférence devra s’insérer dans l’équipe GIBoc de l’Institut des Sciences du Mouvement (ISM, UMR 7287) dont les activités de recherche concernent des études multi-échelles et pluridisciplinaires dans le domaine de la biomécanique ostéoarticulaire.

La personne recrutée viendra renforcer les actions de recherche menées dans le domaine de la bioingénierie des tissus et des implants. Sa mission sera de contribuer au développement de compétences axées vers la modélisation et/ou l’expérimentation des matériaux et structures biologiques ou des biomatériaux.

Le candidat devra avoir des compétences en :
– modélisation du comportement des corps déformables
– calcul des structures
– expérimentation mécanique

Une expérience en biomécanique sera appréciée.

Le maître de conférences devra participer à l’animation scientifique de l’équipe, renforcer son ancrage au sein des réseaux nationaux et s’impliquer dans le développement de partenariats institutionnels et industriels, notamment internationaux.

Profil enseignement :

Objectifs pédagogiques et besoins d’encadrement :
– au sein de la faculté des sciences du sport, les besoins en enseignements en mécanique, mathématiques et biomécaniques sont importants et en particulier en licence. Le maître de conférences recruté enseignera ces matières en Licence STAPS (L1, L2, L3) et pourra être amenée à intervenir en Master.
– le candidat sera amené à encadrer des étudiants de licence, de master (M1 et M2) de la faculté des sciences du sport dans le domaine de la biomécanique.

 

 

Renseignements : patrick.chabrand@univ-amu.fr

 

 


 Ingenieur_recherche_plateforme_microscopeLa plateforme de Microscopie du Centre Méditerranéen de Médecine Moléculaire (Université de NICE SOPHIA ANTIPOLIS) recrute actuellement un ingénieur en expérimentation et en instrumentation biologique dans le cadre d’un CDD d’un an (renouvelable 2 ans) à pourvoir dès que possible.
Le poste est basé à Nice.

 

Activités essentielles :
– Gérer le bon fonctionnement de la plateforme (commandes, accès aux équipements, documents de suivis…).
– Conseiller les utilisateurs du service (élaboration des expériences de microscopie, mise en oeuvre et analyse).
– Former et encadrer les utilisateurs à l’utilisation des équipements de la plateforme et aux outils d’analyse.
– Maintenir de façon régulière l’ensemble des appareils du service dans un état de marche optimisé.
– Développer, proposer de nouvelles méthodologies en adéquation avec les besoins des utilisateurs.
– Participer à des formations en microscopie (formation continue, école doctorale…).
– Participer activement à la démarche qualité des services communs du C3M (norme ISO9001 : 2008).

 

Click here for more information

 


Genetics and genomics of muscle postdoctoral fellowship

 

The Genetics and Genomics of Muscle Training Program will award one postdoctoral position for a three year time period. This T32 Training Award is made available through the National Institute Of Arthritis And Musculoskeletal And Skin Diseases (NIAMS), and located at the Research Center for Genetic Medicine. Children’s National Medical Center, Washington DC. The Center is associated with George Washington University Department of Integrative Systems Biology. An award will provide each Scholar with an integrated didactic and mentored research training program in genomics/genetic research, principles and techniques and a research experience that utilizes genetics, genomics and proteomics to study muscle function and disorders. Please see the link below for GenMed Technologies and tools and Research Programs information. We are seeking cutting edge research candidates with training in genome-enabled studies of muscle, such as GWAS, mRNA profiling, proteomic profiling, and systems biology. PhDs and MDs can be supported for three years. Trainees must be US citizens or hold a “green card” at the time of appointment. Interested individuals should send an application to Terence Partridge, Program Director Terry Partridge and cc Marie Pichaske.

 

Click here for more information

 


 

Logo Institut Pasteur

Funded postdoctoral position at the Institut Pasteur – Paris:
Neuro-inflammation during sepsis and development of neuro-protective strategies

 

The Human Histopathology and Animal Models Unit of the Institut Pasteur (Paris), headed by Prof. Fabrice Chretien, has a position available for a highly motivated postdoctoral scientist to further our research in the pathophysiology of neuro-inflammation during sepsis and its long-term consequences allowing development of neuro-protective strategies.

The successful candidate will investigate how inert molecules modulate microglial reactivity during peripheral sepsis using morphological, functional and metabolic approaches in in vivo models. In close contact with hospital researchers s/he will investigate behavioral and tissue consequences in order to design clinical studies.

 

Click here for more information

 


 

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Post‐doctoral position ‐ Myology Centre for Research ‐ Paris, France

 

A three‐year post‐doctoral position is available under the supervision of Stéphanie Lorain to join the team “RNA‐repair based therapeutics & skeletal muscle pathophysiology” headed by France Piétri‐Rouxel in the Myology Centre for Research. Our goal is the development and optimization of innovative therapeutic approaches to cure Duchenne muscular dystrophy.

Located on the site of La Pitié‐Salpétrière university hospital (75013 Paris, France), the Myology Centre for Research directed by Gillian Butler‐Browne is a center of excellence for multidisciplinary research on the muscle and its pathologies (http://www.institut‐myologie.org/en/recherche‐2/centre‐de‐recherche‐en‐myologie).

A PhD in biomedical sciences or related disciplines is required. Previous experience in translational research in the field of genetic diseases with viral vectors and/or animal models of disease is preferred.

The candidate should be able to work autonomously and a good publication record is mandatory. The candidate should send to Stéphanie Lorain (stephanie.lorain@upmc.fr) a cover letter with a brief statement of research experience, technical expertise and interests.

Click here to download the application


logo_um

Affectation : POLE BIOLOGIE-PATHOLOGIE – 4071 – LABORATOIRE DE GENETIQUE IURC

Grade : INGENIEUR HOSPITALIER.

Le laboratoire de génétique moléculaire du CHRU de Montpellier (Pr Michel Koenig) recrute un Ingénieur Hospitalier à temps plein.

Il s’agit d’un poste à double fonction (chacune sur 1/2 ETP) :
1) Ingénieur de laboratoire dans le groupe des Myopathies (Dr Mireille Cossée)
2) Ingénieur référent qualité dans la cellule qualité (poste transversal)

Description des tâches :

1) Ingénieur dans le groupe Myopathies

– Mises au point de nouvelles technologies appliquées au diagnostic moléculaire des pathologies étudiées dans le groupe, notamment technologies de séquençage haut débit.
– Participation à l’amélioration des techniques utilisées au laboratoire, en interaction avec les techniciens et le biologiste du groupe
– Participation à l’encadrement des techniciens, Internes et stagiaires
– Participation à l’écriture de demandes de financements en rapport avec son activité ou celle du groupe, à la diffusion des résultats (posters, présentations orales, articles scientifiques)

2) Référent qualité du laboratoire

– Management de la qualité en relation avec le RQA: animation des réunions (cellule qualité, diagnostic..), pilotage des groupes de travail, audit interne, revue de direction…
– Coordination du plan d’action qualité du laboratoire, suivi des objectifs et des indicateurs
– Gestion documentaire du système qualité : maîtrise du logiciel de gestion de Qualité, veille documentaire, gestion du cycle de vie des documents…

 

Cliquez ici pour voir l’annonce complète


Post-doc_add_BNMS

Post‐doctoral positions are available in the team directed by Pr Frédéric Relaix at Mondor Institute of Biomedical Research (IMRB) in Paris‐Est, France.

The candidates will be involved in (1) analysing the impact of obesity and inflammation for muscle stem cells biology during skeletal muscle growth, regeneration and aging, (2) Perform preclinical modelling and therapeutic research in skeletal muscle diseases, including sarcopenia in obese patients. In addition the candidate will help to train ad supervise Master and PhD students.

 

 

Click Here for more information


Nestlé Institute of Health Science

The Nestlé Institute of Health Sciences (NIHS) has recently been established to deliver world class excellence in biomedical research to better understand health and disease as influenced by genetics, metabolism and environment with the goal of translating this knowledge into personalized science-based nutrition.

Demonstrating excellent result focus and proactive cooperation, you will be working in a dynamic, multi-cultural and interdisciplinary research environment. In this role you will be contributing experimentally to research projects and optimizing the lab organization to achieve higher productivity.

Key responsibilities
– Isolation and culture of primary myoblasts.
– Set-up and run image-based cellular assays.
– Support muscle stem cell projects with molecular and cellular biology techniques (DNA/RNA extraction, immunostaining, electrophoresis, quantitative PCR, confocal and light microscopy).
– Design experiments, analyze data and communicate results.
– Participate in operational activities of the lab (maintenance of equipment, purchasing, safety).

 

Click here for more information

 


 

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Postdoctoral position in musculoskeletal regeneration and stem cells

Institut national de la sante et de la recherche medicale Inserm umr1163, institut imagine, paris, france

We are seeking applicants for a Postdoctoral Scholar position to join the Laboratory of Skeletal Regeneration at INSERM UMR1163, Institut Imagine, Paris, France.

Click Here for more Information

 


 

Institut-Neuroscience-Grenoble

Call for Junior and Senior Group Leaders

 

The Grenoble Institute of Neurosciences (GIN), an outstanding research center devoted to understanding brain functions and the development of innovative clinical therapies for neurological, neuromuscular and psychiatric disorders, is welcoming applications for positions as junior and senior group leaders in basic and/or clinical research.

Junior positions: the Institute is offering a start-up package and laboratory space for up to 6 persons. Candidates should hold a PhD and/or an MD degree, have strong postdoctoral experience and meet criteria to obtain national (ANR, Atip-Avenir, FRM Amorçage, etc.) and international funding, and a French research institutional position (Inserm, CNRS).

Senior positions: the Institute is offering a start up package and laboratory space for up imaging center (PIC-GIN), and electron microscopy providing the necessary resources for high standard and innovative research.

Click Here to Download the Application Form